Whereas many earthquakes on Earth occur at depths less than 60 km, around 25 % happen at larger depths of up 700 km. Despite their distance from the surface, large deep earthquakes represent a considerable seismic hazard. These earthquakes are particularly intriguing, as unattainably large forces are required to break rocks at those depths, a problem that was already recognized by K. Wadati in 1928. In the 90 years that passed since, different hypotheses have surfaced to explain these events, but despite the wealth of observational data and laboratory experiments, the underlying nucleation and rupture mechanisms of deep earthquakes remain enigmatic. To solve this long-standing problem, QuakeID will employ an interdisciplinary approach with numerical modelling at its core. Numerical simulations will be combined with novel laboratory experiments and seismological observations, to upscale results from the laboratory to the Earth. For this, cutting edge numerical models will be developed that can be applied at both seismic and geological time scales to model deep earthquake rupture. Together with specifically designed high pressure/high temperature experiments, they will be used to